Valproic Acid (DEPAMAX® SYRUP)
What is Depamax syrup used for?
Depamax syrup is an antiepileptic drug used as monotherapy and adjunctive therapy in the treatment of patients with complex partial seizures that occur in isolation or in association with other types of seizures. It is also indicated for sole and adjunctive therapy for simple and complex absence seizures and adjunctively in patients with multiple seizure types.
How much and how often should Depamax syrup be taken?
Complex Partial Seizures in Children ten years of age & older. Monotherapy: Initiate therapy at 10-15 mg/kg/day. Dosage may be increased by 5 to 10 mg/kg/week to achieve optimal clinical response. Maximum dose is 60 mg/kg/day. Adjunctive Therapy: Depamax may be added to the patient’s regimen at a dose of 10 to 15 mg/kg/day.
Simple & Complex Absence Seizures: Recommended initial dose is 15 mg/kg/day. Increase at one-week intervals by 5 to 10 mg/kg day until seizures are controlled. Maximum recommended dosage is 60 mg/kg/day. If total daily dose exceeds 250 mg, it should be given in divided doses.
What are the possible side effects of Depamax syrup?
Possible side effects of Depamax syrup are decreased platelets, elevated liver enzymes, gastric irritation, rashes & somnolence.
What is the available pack size of Depamax syrup?
Depamax syrup is valproic acid 250 mg/5 mL syrup available in 100 mL in box of 1’s.
FDA Registration number:
250 mg / 5 mL: DRP-8060-03